THE HYPOXIA-DRIVEN CROSSTALK BETWEEN TUMOR AND TUMOR-ASSOCIATED MACROPHAGES: MECHANISMS AND CLINICAL TREATMENT STRATEGIES

The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME), which have a large may pride peach tree i

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Isolated Fetal Ascite Associated with Cardiac Diseases

Fetal ascite is defined as fluid butterfly cupcake liners accumulation in peritoneal cavity.It can be seen as isolated disease or an early sign of hydrops fetalis.Once fetal ascite is detected, a careful examination for hydops fetalis and possible underlying disease is necessary, since its prognosis and treatment depends mostly on the cause.Non-imm

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Current and previous spatial distributions of oilseed rape fields influence the abundance and the body size of a solitary wild bee, Andrena cineraria, in permanent grasslands.

Wild bees are essential pollinators whose survival partly depends on the capacity of their environment to offer a sufficient amount of nectar and pollen.Semi-natural habitats and mass-flowering crops such as oilseed rape provide abundant floristic resources for bees.The aim of this study was to evaluate the influences of the spatial distribution of

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Appropriate practice of anesthesia: A plea for better training

Background: The role of the anesthesiologist is often unknown among patients.But, the situation where the anesthesiologist is uncertain of his/her function gives more cause for concern.Methods: A questionnaire survey on the appraisal of anesthetic practices was carried out over 5 months using the style of clinical practice.Results: One-third of the

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